January 13, 2022

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The Nobel Prize in Medicine is awarded to two scientists who discovered how heat and touch receptors work

Two American scientists won the 2021 Nobel Prize in Medicine for discovering the way our bodies feel the heat of the sun or the hug of a lover.

David Julius and Ardem Patbutian, from the United States, will share this year’s Nobel Prize in Medicine or Physiology for their studies in the body’s sense of touch and temperature.

The two scientists discovered how our bodies convert sensations into electrical messages in the nervous system.

Their findings may lead to the development of new ways to treat pain.

Heat, cold, and touch are essential to adapting to the world around us, and for our survival.

However, the way our bodies actually sense touch and heat has been one of the greatest mysteries in biology.

“This is a very important and profound discovery,” said Thomas Perelman of the Nobel Prize Committee.

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David Julius and Erdem Patbutian, from the United States, will share the 2021 Medicine Prize

The achievement by David Julius, at the University of California, San Francisco, was based on monitoring and studying the burning pain we feel from eating hot peppers.

He conducted an experiment using the heat source of hot peppers, the chemical element capsaicin.

And he discovered a specific type of receptor (part of our cells) that responds to capsaicin.

Other experiments showed that the receptors respond to heat and are affected by “excruciating” temperatures, which is what happens, for example, if you burn your hand with a cup of coffee.

This discovery led to the discovery of many other temperature receptors, as Julius and Erdem Patbutian spotted one of the sensors or receptors that can detect colds.

Meanwhile, Patabotian, who works at the Scripps Research Institute, was also studying these cells.

Those experiments led to the discovery of a different type of receptor that activated in response to mechanical force or touch.

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The chemical in hot peppers, which causes the burning sensation, played a crucial role in the discovery of the first heat-sensing receptor

When you walk on a beach and feel sand under your feet, it is these receptors that send signals to the brain.

These touch and temperature sensors have demonstrated a wide-ranging role in the body and in some diseases.

The first temperature sensor (called TRPV1) also plays a role in chronic pain and how the body regulates its core temperature, and the tactile receptor (PIEZ02) has multiple roles, from urination to blood pressure.

The prize committee said the study “allowed us to understand how heat, cold and mechanical force can stimulate the nerve impulses that allow us to perceive and adapt to the world around us.”

“This science is used to develop treatments for a wide range of conditions, including chronic pain,” she added.

The two scientists will share the 10 million Swedish crowns (£845,000) prize.